Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957311 | 0.83 | METTL3 (0.43) | METTL3MAPTGAATP53 | |
| SCHEMBL13862201 | 0.80 | METTL3 (0.43) | METTL3 | |
| SCHEMBL13862193 | 0.79 | METTL3 (0.47) | METTL3 | |
| SCHEMBL14611461 | 0.78 | METTL3 (0.64) | METTL3MAPTGAAPLA2G4ATP53 | |
| SCHEMBL13472097 | 0.78 | METTL3 (0.49) | METTL3 | |
| SCHEMBL13250854 | 0.78 | METTL3 (0.49) | METTL3 | |
| SCHEMBL1045839 | 0.77 | METTL3 (0.79) | METTL3MAPTGAAPLA2G4ATP53 | |
| SCHEMBL1045841 | 0.77 | METTL3 (0.79) | METTL3MAPTGAAPLA2G4ATP53 | |
| SCHEMBL11948687 | 0.77 | METTL3 (0.69) | METTL3MAPTGAAPLA2G4ATP53 | |
| SCHEMBL3234873 | 0.76 | METTL3 (0.66) | METTL3MAPTGAAPLA2G4ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531554-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2009-05-12 | — | — | US | disclosed |