Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862592 | 0.87 | L3MBTL1 (0.44) | LMNAKDM4EHSD17B10PDE7AL3MBTL1 | |
| SCHEMBL2892860 | 0.80 | SLC6A2 (0.50) | LMNAKDM4EHSD17B10L3MBTL1GAA | |
| SCHEMBL13862601 | 0.80 | IDH1 (0.43) | KDM4EHSD17B10L3MBTL1MAPTKMT2A | |
| SCHEMBL2888424 | 0.76 | HTR2A (0.45) | LMNAKDM4EHSD17B10L3MBTL1GAA | |
| SCHEMBL9119625 | 0.72 | KDM4E (0.60) | LMNAHDAC1KDM4EHSD17B10GAA | |
| SCHEMBL2890443 | 0.71 | KDM4E (0.58) | LMNAHDAC1KDM4EHSD17B10MAPT | |
| SCHEMBL4311940 | 0.70 | KDM4E (0.66) | LMNAKDM4EHSD17B10GAASMN1; SMN2 | |
| SCHEMBL29822237 | 0.70 | KDM4E (0.66) | LMNAKDM4EHSD17B10GAASMN1; SMN2 | |
| SCHEMBL2890509 | 0.70 | SLC6A2 (0.46) | LMNAKDM4EL3MBTL1GAAMAPT | |
| SCHEMBL6301593 | 0.70 | HDAC1 (0.54) | LMNAHDAC1HDAC8HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066072-A2 | COMPOUND | STERIX LIMITED (GB) | 2009-05-28 | — | — | WO | disclosed |