Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890443 | 0.88 | KDM4E (0.58) | KDM4EHSD17B10HDAC1USP2HPGD | |
| SCHEMBL12101718 | 0.87 | NPC1 (0.51) | KDM4EHSD17B10HDAC1KMT2AMAPT | |
| SCHEMBL23524965 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10HPGDKMT2AMAPT | |
| SCHEMBL23434997 | 0.83 | HSD17B10 (0.54) | KDM4EHSD17B10HDAC1USP2HPGD | |
| SCHEMBL21791607 | 0.83 | ALDH1A1 (0.53) | KDM4EUSP2HPGDKMT2AMAPT | |
| SCHEMBL12074983 | 0.83 | HPGD (0.50) | KDM4EUSP2HPGDKMT2AMEN1 | |
| SCHEMBL11407433 | 0.83 | ALDH1A1 (0.51) | KDM4EHSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL1646158 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10HDAC1USP2HPGD | |
| SCHEMBL5107971 | 0.82 | MTNR1A (0.56) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7871930 | 0.81 | NPC1 (0.61) | KDM4EHSD17B10HDAC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3012258-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS | Gilead Sciences, Inc. (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2585467-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2016-03-02 | — | — | EP | disclosed |
| US-5422211-A | Imaging members with trisazo photogenerating materials | XEROX CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |