SCHEMBL13863

SCHEMBL13863

Nc1nc[nH]c(=O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1094924 0.98
Hydrochloric Acid SCHEMBL11693353 0.98
SCHEMBL3505913 0.89 ALDH1A1 (0.37)
SCHEMBL29261403 0.79 ALDH1A1 (0.31)
Guanine SCHEMBL19974408 0.78 ALDH1A1 (0.50)
SCHEMBL11910496 0.76
Ribose (Furanose) SCHEMBL346135 0.74 LMNA (0.49)
Ribose (Furanose) SCHEMBL10787751 0.74 LMNA (0.49)
SCHEMBL10532516 0.74 PNP (0.38)
Xylose SCHEMBL28731770 0.73 PNP (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4240 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US claimed
EP-4729063-A2 TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES BPGbio, Inc. (US) 2026-04-22 EP claimed
EP-3458464-B1 STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES ETH ZUERICH (CH) 2026-04-15 EP claimed
US-12559515-B2 Cap compounds and RNAS comprising the same HELIX NANOTECHNOLOGIES INC (US) 2026-02-24 US claimed
US-20250353838-A1 METHOD FOR PREPARING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE PINOTBIO, INC. (KR) 2025-11-20 US claimed
WO-2025199647-A1 C4'-MODIFIED NUCLEOSIDE ANALOGUES AND SYNTHETIC METHODS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-10-02 WO claimed
WO-2025137486-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC (US) 2025-06-26 WO claimed
US-20250206770-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC 2025-06-26 US claimed
CN-116103008-B Strippable polyurethane hot melt adhesive based on reactive extrusion and synthesis method thereof 郑州大学 2025-03-21 CN claimed
EP-4524145-A1 METHOD FOR PREPARING 4?-THIO-5-AZA-2?-DEOXYCYTIDINE Pinotbio, Inc. (KR) 2025-03-19 EP claimed
US-4806542-A VIRISTATICS, IMMUNOSTIMULANTS HEINRICH MACK NACHF. (DE) 1989-02-21 US claimed
EP-0243670-A1 Purine and pyrimidine compounds and their use as anti-viral agents SYNTEX (U.S.A.) INC. (US) 1987-11-04 EP claimed
EP-0234494-A2 Isohexide nucleosides, processes for their preparation and their use as medicaments Heinrich Mack Nachf. (DE) 1987-09-02 EP claimed
EP-0183843-A1 THIOPHOSPHOLIPID CONJUGATES OF ANTITUMOR AGENTS HEALTH RESEARCH, INC. (US) 1986-06-11 EP claimed
WO-1986000309-A1 THIOPHOSPHOLIPID CONJUGATES OF ANTITUMOR AGENTS HEALTH RESEARCH INC. (US) 1986-01-16 WO claimed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP claimed
US-4291024-A ANTICANCER AGENTS UNIVERSITY OF RHODE ISLAND 1981-09-22 US claimed
EP-0033341-A1 CYTOTOXIC NUCLEOSIDE-CORTICOSTEROID PHOSPHODIESTERS Research Corporation (US) 1981-08-12 EP claimed
US-4283394-A ANTICARCINOGENIC AGENTS RESEARCH CORPORATION (US) 1981-08-11 US claimed
WO-1981000410-A1 CYTOTOXIC NUCLEOSIDE-CORTICOSTEROID PHOSPHODIESTERS RESEARCH CORP (US) 1981-02-19 WO claimed