Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | FURIN | P09958 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863176 | 1.00 | GAA (0.51) | GAAMEN1KMT2AFURINHDAC4 | |
| SCHEMBL7044331 | 0.95 | MEN1 (0.54) | GAAMEN1KMT2AFURINHDAC4 | |
| SCHEMBL5974478 | 0.89 | FURIN (0.55) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL5973841 | 0.89 | FURIN (0.55) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL5974904 | 0.89 | FURIN (0.55) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL5974680 | 0.89 | FURIN (0.55) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL4914693 | 0.89 | FURIN (0.55) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL5974764 | 0.87 | HDAC3 (0.54) | MEN1KMT2AFURINHDAC4HDAC1 | |
| SCHEMBL5973806 | 0.84 | FURIN (0.54) | GAAMEN1KMT2AFURINHDAC4 | |
| SCHEMBL11989953 | 0.84 | HDAC1 (0.62) | HDAC4HDAC1HDAC7HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722620-B2 | Insulin derivatives | NOVO NORDISK A/S (DK) | 2014-05-13 | — | — | US | disclosed |
| US-20090137454-A1 | Insulin Derivatives | NOVO NORDISK A/S (DK) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137454-A1 | Insulin Derivatives | IAPP, INSR, GPR119 | GAA 408/4885MEN1 626/4885KMT2A 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.