Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385405 | 0.92 | MDM4 (0.47) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL12677569 | 0.88 | MDM4 (0.49) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29047045 | 0.88 | MDM4 (0.49) | MDM4TP53CASP3KMT2A | |
| SCHEMBL29367497 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL119565 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL598209 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL29624621 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL119575 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL29355082 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 | |
| SCHEMBL30802551 | 0.86 | MDM4 (0.56) | MDM4TP53CASP3MDM2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531506-B2 | Process for producing trunkamide a compounds | PHARMA MAR, S.A. (ES) | 2009-05-12 | — | — | US | disclosed |