Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385518 | 0.92 | EDNRB (0.73) | EDNRBEDNRA | |
| SCHEMBL1386066 | 0.88 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL5764942 | 0.86 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL4070738 | 0.83 | EDNRA (0.68) | EDNRBEDNRA | |
| SCHEMBL5764866 | 0.80 | EDNRA (0.88) | EDNRBEDNRA | |
| SCHEMBL1383706 | 0.79 | EDNRA (0.88) | EDNRBEDNRA | |
| SCHEMBL8801739 | 0.79 | EDNRB (0.73) | EDNRBEDNRA | |
| SCHEMBL1384143 | 0.78 | EDNRA (0.85) | EDNRBEDNRA | |
| SCHEMBL13747832 | 0.77 | EDNRA (0.84) | EDNRBEDNRA | |
| SCHEMBL1386375 | 0.77 | EDNRA (0.84) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4832706-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1309564-B1 | ARYLETHENE-SULFONAMIDES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-14 | — | — | EP | claimed |