Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068362 | 0.85 | EDNRB (0.75) | EDNRAEDNRB | |
| SCHEMBL1386495 | 0.83 | EDNRB (0.75) | EDNRAEDNRB | |
| SCHEMBL8801739 | 0.80 | EDNRB (0.73) | EDNRAEDNRB | |
| SCHEMBL1386066 | 0.77 | EDNRB (0.58) | EDNRAEDNRB | |
| SCHEMBL4061155 | 0.76 | EDNRB (0.44) | EDNRAEDNRB | |
| SCHEMBL1385518 | 0.75 | EDNRB (0.73) | EDNRAEDNRB | |
| SCHEMBL5501326 | 0.73 | EDNRB (0.89) | EDNRAEDNRB | |
| SCHEMBL4061152 | 0.73 | EDNRB (0.45) | EDNRAEDNRB | |
| SCHEMBL4057566 | 0.73 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4070379 | 0.73 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322624-B1 | ARYLALKANE-SULFONAMIDES HAVING ENDOTHELIN-ANTAGONIST ACTIVITY | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-21 | — | — | EP | claimed |