Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865645 | 0.93 | THRB (0.43) | THRBACACBTSHRHTTFFAR1 | |
| SCHEMBL13865636 | 0.89 | THRB (0.40) | THRBACACBTSHRHDAC1HTT | |
| SCHEMBL13806755 | 0.88 | THRB (0.39) | THRBACACBKDM4EPPARGPPARD | |
| SCHEMBL13869323 | 0.88 | THRB (0.39) | THRBTSHRKDM4EPPARGPPARD | |
| SCHEMBL13865574 | 0.83 | FFAR1 (0.36) | THRBACACBTSHRFFAR1HPGD | |
| SCHEMBL13865601 | 0.83 | ACACB (0.41) | THRBACACBHTTHPGDMAPT | |
| SCHEMBL13865621 | 0.82 | MEN1 (0.43) | THRBTSHRPPARGPPARAHTT | |
| SCHEMBL13869185 | 0.81 | MMP3 (0.46) | THRBHDAC1HPGDMAPT | |
| SCHEMBL12437039 | 0.81 | THRB (0.50) | THRBACACBTSHRKDM4EPPARG | |
| SCHEMBL13865637 | 0.81 | ACACB (0.44) | THRBACACBTSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527746-B2 | Liquid crystal polyfunctional acrylate derivative and polymer thereof | CHISSO CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |