Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506984 | 0.91 | ALDH1A1 (0.51) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13778847 | 0.84 | ALDH1A1 (0.51) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2342658 | 0.81 | ERN1 (0.57) | KDM4EALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL12414900 | 0.78 | ALDH1A1 (0.70) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2096627 | 0.72 | MAPT (0.45) | KDM4EALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL2096629 | 0.72 | MAPT (0.45) | KDM4EALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL22982403 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL344620 | 0.71 | AKR1C3 (0.52) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL344708 | 0.71 | BACE1 (0.54) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL344709 | 0.71 | BACE1 (0.54) | AKR1C3AKR1C2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534751-B2 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534751-B2 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080171681-A1 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | DYKSTRA ROBERT RICHARD | 2008-07-17 | — | — | US | disclosed |
| US-20080171681-A1 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | DYKSTRA ROBERT RICHARD | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171681-A1 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | CUTA, PSAP, PSENEN | AKR1C3 727/4885AKR1C2 1401/4885KDM4E 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.