Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 9/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PAK3 | O75914 | 1/20 | 0.41 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865721 | 0.93 | PAK1 (0.47) | TRPV1TRPM8PAK1KITPAK3 | |
| SCHEMBL13865712 | 0.91 | PAK1 (0.46) | TRPV1TRPM8PAK1KITPAK3 | |
| SCHEMBL13865728 | 0.88 | PAK1 (0.43) | TRPV1TRPM8PAK1KITPAK3 | |
| SCHEMBL13865684 | 0.85 | CYP2C9 (0.49) | TRPV1TRPM8PAK1KITKDM4E | |
| SCHEMBL13865714 | 0.85 | TRPV1 (0.43) | TRPV1TRPM8PAK1KITCA12 | |
| SCHEMBL13865715 | 0.83 | TRPV1 (0.54) | TRPV1PAK1KITEPHX2KDM4E | |
| SCHEMBL13865711 | 0.81 | DRD2 (0.45) | TRPV1TRPM8PAK1CA12CA1 | |
| SCHEMBL13865722 | 0.80 | TRPV1 (0.45) | TRPV1PAK1CA12CA1CA2 | |
| SCHEMBL13865716 | 0.79 | PAK1 (0.42) | TRPV1TRPM8PAK1CA12CA1 | |
| SCHEMBL13870115 | 0.79 | PAK1 (0.49) | TRPV1PAK1EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528151-B2 | Heterocyclic urea derivatives for the treatment of pain | GLAXO GROUP LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |