Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3885657 | 0.93 | DPP4 (0.46) | DPP4DPP9FAPCHRM1KCNH2 | |
| SCHEMBL13866913 | 0.90 | DPP4 (0.43) | DPP4DPP9FAPCHRM1KCNH2 | |
| SCHEMBL13866905 | 0.90 | DPP4 (0.44) | DPP4DPP9FAPKCNH2 | |
| SCHEMBL13866907 | 0.89 | CYP1A2 (0.42) | DPP4DPP9FAPCHRM1USP2 | |
| SCHEMBL13866910 | 0.88 | DPP4 (0.45) | DPP4DPP9FAPCHRM1KCNH2 | |
| SCHEMBL13866909 | 0.87 | DPP4 (0.42) | DPP4DPP9FAPCHRM1KCNH2 | |
| SCHEMBL13866930 | 0.87 | DPP4 (0.47) | DPP4DPP9FAPCHRM1KCNH2 | |
| SCHEMBL13866891 | 0.86 | DPP4 (0.60) | DPP4DPP9FAPCHRM1 | |
| Trifluoroacetic Acid SCHEMBL3873847 | 0.85 | DPP4 (0.41) | DPP4DPP9FAPCHRM1 | |
| Trifluoroacetic Acid SCHEMBL3877491 | 0.85 | DPP4 (0.40) | DPP4DPP9FAPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |