Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.42 |
| ▸ | FAP | Q12884 | 5/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3875903 | 0.93 | DPP4 (0.39) | DPP4FAPDPP9CHRM1P2RX3 | |
| SCHEMBL13866936 | 0.88 | DPP4 (0.40) | DPP4FAPDPP9KCNH2CHRM1 | |
| SCHEMBL13866899 | 0.87 | DPP4 (0.51) | DPP4FAPDPP9KCNH2CHRM1 | |
| SCHEMBL13866966 | 0.85 | DPP4 (0.41) | DPP4FAPDPP9KCNH2CHRM1 | |
| SCHEMBL13866910 | 0.85 | DPP4 (0.45) | DPP4FAPDPP9KCNH2CHRM1 | |
| SCHEMBL13866905 | 0.85 | DPP4 (0.44) | DPP4FAPDPP9KCNH2 | |
| SCHEMBL13866907 | 0.84 | CYP1A2 (0.42) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL13866913 | 0.83 | DPP4 (0.43) | DPP4FAPDPP9KCNH2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL3872972 | 0.82 | DPP4 (0.37) | DPP4FAPDPP9CHRM1 | |
| Trifluoroacetic Acid SCHEMBL3885657 | 0.81 | DPP4 (0.46) | DPP4FAPDPP9KCNH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |