Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 6/20 | 0.42 |
| ▸ | CASP7 | P55210 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 9/20 | 0.42 |
| ▸ | USP2 | O75604 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3882040 | 0.93 | DPP4 (0.39) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13866899 | 0.89 | DPP4 (0.51) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13866905 | 0.88 | DPP4 (0.44) | DPP4FAPDPP9 | |
| SCHEMBL13866910 | 0.85 | DPP4 (0.45) | DPP4FAPCHRM1DPP9 | |
| SCHEMBL13866909 | 0.84 | DPP4 (0.42) | DPP4FAPCHRM1DPP9 | |
| SCHEMBL13866913 | 0.83 | DPP4 (0.43) | DPP4FAPCHRM1DPP9 | |
| Trifluoroacetic Acid SCHEMBL3885657 | 0.83 | DPP4 (0.46) | DPP4FAPCHRM1DPP9 | |
| Trifluoroacetic Acid SCHEMBL3877491 | 0.82 | DPP4 (0.40) | DPP4FAPDPP9 | |
| SCHEMBL13866930 | 0.82 | DPP4 (0.47) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13866842 | 0.81 | DPP4 (0.61) | DPP4FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |