Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844 | 1.00 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL35887 | 1.00 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL35888 | 1.00 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL17041334 | 1.00 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL2049696 | 1.00 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL20262981 | 0.97 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| Hydrochloric Acid SCHEMBL7641498 | 0.97 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| Ammonia Solution, Strong SCHEMBL21463027 | 0.97 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL6740705 | 0.97 | ANPEP (0.50) | ACETSHRSLC6A1SLC6A11LMNA | |
| Bromide SCHEMBL7786835 | 0.97 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538131-B2 | 2-{-3-′2-(phenyl)-oxazol-4-ylmethoxymethyl-cyclohexylmethoxy}-propionic acid derivatives useful as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-26 | — | — | US | disclosed |