Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.46 |
| ▸ | SLC6A1 known ✓ | P30531 | 2/20 | 0.46 |
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.42 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.42 |
| ▸ | GABRE known ✓ | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 known ✓ | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ known ✓ | Q9UN88 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7641498 | 1.00 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL29844 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL35887 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL13868097 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL2049696 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL17041334 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL35888 | 0.97 | ACE (0.48) | ACETSHRSLC6A1SLC6A11LMNA | |
| Ammonia Solution, Strong SCHEMBL21463027 | 0.94 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| SCHEMBL20262981 | 0.94 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA | |
| Bromide SCHEMBL7786835 | 0.94 | ACE (0.46) | ACETSHRSLC6A1SLC6A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118142347-A | Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer | 中国石油大学(华东) | 2024-06-07 | — | — | CN | claimed |
| EP-1149836-B1 | Polynalbuphine derivatives | HU OLIVER YOA PU (TW) | 2003-02-26 | — | — | EP | claimed |
| EP-1149836-A1 | Polynalbuphine derivatives | Hu, Oliver Yoa-Pu (TW) | 2001-10-31 | — | — | EP | claimed |
| US-20240335796-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2024-10-10 | — | — | US | disclosed |
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2024-07-16 | — | — | US | disclosed |
| CN-118142347-A | Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer | 中国石油大学(华东) | 2024-06-07 | — | — | CN | disclosed |
| US-11926127-B2 | Window film for display device and display device including same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2024-03-12 | — | — | US | disclosed |
| CN-116802774-A | Hollow microsphere | 株式会社德山 | 2023-09-22 | — | — | CN | disclosed |
| EP-3476592-B1 | MULTILAYER FILM | TORAY INDUSTRIES (JP) | 2023-06-14 | — | — | EP | disclosed |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
| CN-109311287-B | Laminated film | 东丽株式会社 | 2021-08-24 | — | — | CN | disclosed |
| EP-0316960-A2 | Gas separation membranes from bisphenol af polycarbonates and polyestercarbonates | THE DOW CHEMICAL COMPANY (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0244126-A2 | Tetrabromo bisphenol based polyestercarbonate membranes and method of using | THE DOW CHEMICAL COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0036629-B1 | MELT PROCESSABLE POLY(ESTER CARBONATE) WITH HIGH GLASS TRANSITION TEMPERATURE | ALLIED CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0017740-B1 | PREPARATION OF POLY(ESTER CARBONATE) BY INTERFACIAL METHOD | ALLIED CORPORATION (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4310652-A | Melt processable poly(ester carbonate) with high glass transition temperature | ALLIED CHEMICAL CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0036629-A1 | Melt processable poly(ester carbonate) with high glass transition temperature | ALLIED CORPORATION (US) | 1981-09-30 | — | — | EP | disclosed |
| EP-0027844-A1 | Poly(ester carbonate) with high glass transition temperature | ALLIED CORPORATION (US) | 1981-05-06 | — | — | EP | disclosed |
| US-4255556-A | Preparation of poly(ester carbonate) by interfacial method | ALLIED CHEMICAL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0017740-A1 | Preparation of poly(ester carbonate) by interfacial method | ALLIED CORPORATION (US) | 1980-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335796-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | ACE 4348/4885SLC6A1 1561/4885GABRP 3466/4885 |
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | PORCN, MLEC, FLOT1 | ACE 4348/4885SLC6A1 1561/4885GABRP 3466/4885 |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | ACE 4348/4885SLC6A1 1561/4885GABRP 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.