Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868204 | 0.88 | BTK (0.52) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL7731684 | 0.88 | BTK (0.46) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL7727313 | 0.88 | BTK (0.46) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL7727315 | 0.88 | BTK (0.46) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL13868206 | 0.86 | CTSK (0.48) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL29243383 | 0.82 | CTSK (0.51) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL7729577 | 0.81 | CTSK (0.48) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL7726769 | 0.81 | CTSK (0.48) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL25271337 | 0.80 | CYP3A4 (0.44) | NR1H2NR1H3PTPN1EPHX1 | |
| SCHEMBL10058227 | 0.80 | CYP3A4 (0.44) | NR1H2NR1H3PTPN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | CTSK 1600/4885BTK 953/4885CA1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.