Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22559082 | 0.81 | MAPT (0.41) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3585800 | 0.80 | MAPT (0.49) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL841568 | 0.78 | CYP1A2 (0.61) | MAPTHTTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3218972 | 0.77 | NPC1 (0.53) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL2255366 | 0.77 | MAPT (0.49) | MAPTHTTALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL11188965 | 0.76 | USP2 (0.52) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL1292324 | 0.75 | MAPT (0.44) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL4218771 | 0.75 | MAPT (0.44) | MAPTLMNAHTTALDH1A1S1PR2 | |
| SCHEMBL12317147 | 0.75 | HTT (0.49) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL22971083 | 0.75 | GRM5 (0.50) | MAPTHTTALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524860-B2 | Antibacterial agents | PFIZER INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524860-B2 | Antibacterial agents | PFIZER INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080021059-A1 | Antibacterial Agents | PFIZER INC. (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080021059-A1 | Antibacterial Agents | PFIZER INC. (US) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021059-A1 | Antibacterial Agents | CLPP, QDPR, CLSPN | MAPT 3993/4885LMNA 4674/4885HTT 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.