Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021642 | 0.83 | L3MBTL1 (0.40) | MAPTKDM4EALDH1A1MEN1POLB | |
| SCHEMBL369000 | 0.83 | L3MBTL1 (0.40) | MAPTKDM4EALDH1A1MEN1POLB | |
| SCHEMBL9556471 | 0.80 | CYP1A2 (0.45) | MAPTKDM4EALDH1A1TP53GAA | |
| SCHEMBL13882478 | 0.79 | KMT2A (0.46) | KDM4EALDH1A1MEN1USP2POLB | |
| SCHEMBL13868964 | 0.79 | KMT2A (0.46) | KDM4EALDH1A1MEN1USP2POLB | |
| SCHEMBL13868967 | 0.79 | KDM4E (0.39) | MAPTKDM4EL3MBTL1TDP1 | |
| SCHEMBL23267299 | 0.77 | L3MBTL1 (0.55) | MAPTKDM4EALDH1A1GAAPOLB | |
| SCHEMBL1778304 | 0.77 | THRA (0.49) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1776059 | 0.77 | THRA (0.49) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2831022 | 0.77 | THRA (0.49) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521232-B2 | Emissive species for clinical imaging | ICX NOMADICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20070281289-A1 | Emissive species for clinical imaging | NOMADICS, INC. (US) | 2007-12-06 | — | — | US | disclosed |