Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869472 | 0.77 | ALDH1A1 (0.41) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869810 | 0.74 | MEN1 (0.34) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869292 | 0.73 | SMN1; SMN2 (0.35) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869244 | 0.72 | ADORA3 (0.60) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869492 | 0.71 | CYP19A1 (0.59) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869516 | 0.69 | ALDH1A1 (0.58) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869496 | 0.69 | ALDH1A1 (0.42) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869814 | 0.69 | MAPT (0.60) | RAB9AALDH1A1KDM4EMAOBMEN1 | |
| SCHEMBL15398176 | 0.68 | ADORA1 (0.67) | RAB9AALDH1A1KDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13869474 | 0.68 | MAPT (0.59) | RAB9AALDH1A1KDM4EMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |