Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003975 | 0.90 | KMT2A (0.48) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL17243734 | 0.88 | BCL9 (0.46) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL13239069 | 0.86 | HDAC8 (0.43) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL13345755 | 0.85 | KMT2A (0.44) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL12061383 | 0.81 | LMNA (0.53) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL18471992 | 0.80 | LMNA (0.69) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL17243982 | 0.79 | LMNA (0.54) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL28462762 | 0.79 | ALB (0.62) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL18380781 | 0.79 | ALB (0.62) | KMT2AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL28469011 | 0.77 | ESR1 (0.64) | KMT2AMAPTLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521584-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |