Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243982 | 0.92 | LMNA (0.54) | BCL9CTNNB1KMT2AKDM4ELMNA | |
| SCHEMBL14003975 | 0.88 | KMT2A (0.48) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL13869475 | 0.88 | KMT2A (0.58) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL13345755 | 0.86 | KMT2A (0.44) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL13239069 | 0.85 | HDAC8 (0.43) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL20581562 | 0.84 | KMT2A (0.64) | BCL9CTNNB1KMT2AKDM4ELMNA | |
| SCHEMBL19873148 | 0.83 | KMT2A (0.53) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL1042498 | 0.83 | PTGS2 (0.56) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL19873140 | 0.82 | KMT2A (0.55) | KMT2AKDM4ELMNAMAPTMEN1 | |
| SCHEMBL18471992 | 0.81 | LMNA (0.69) | KMT2AKDM4ELMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180111-B2 | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof | CARDAX PHARMA, INC. (US) | 2015-11-10 | — | — | US | disclosed |