Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12135548 | 0.79 | HMGCR (0.40) | MEN1KMT2AKDM4E | |
| SCHEMBL27266707 | 0.79 | LMNA (0.40) | PKMMEN1KMT2APOLBKDM4E | |
| SCHEMBL761032 | 0.78 | PKM (0.56) | PKMABCB1MEN1KMT2APOLB | |
| SCHEMBL12026674 | 0.76 | NPSR1 (0.58) | POLBKDM4EL3MBTL1 | |
| SCHEMBL8986670 | 0.76 | HMGCR (0.41) | MEN1KMT2AKDM4E | |
| SCHEMBL12026672 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12026670 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10056780 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28123602 | 0.74 | PKM (0.56) | PKMABCB1MEN1KMT2APOLB | |
| SCHEMBL10110611 | 0.74 | HMGCR (0.36) | PKMMEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514500-B2 | Complexing resins and method for preparation thereof | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2009-04-07 | — | — | US | disclosed |