Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869266 | 0.84 | ALDH1A1 (0.66) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869536 | 0.83 | MAPT (0.49) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869796 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869335 | 0.82 | ALDH1A1 (0.64) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869249 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869508 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869798 | 0.81 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869286 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869799 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL4379904 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |