Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869795 | 0.83 | KDM4E (0.53) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL13869266 | 0.77 | ALDH1A1 (0.66) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL17152014 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HPGDTSHRHSD17B10MEN1 | |
| SCHEMBL13869775 | 0.76 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL13869335 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL19131575 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL13869554 | 0.76 | KDM4E (0.50) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL19132267 | 0.76 | PGR (0.35) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL19824449 | 0.76 | PGR (0.39) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL12133788 | 0.75 | ENPP1 (0.42) | MAPTALDH1A1KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |