Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | ATM | Q13315 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869789 | 0.83 | MAPT (0.49) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13886347 | 0.82 | MAPT (0.36) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869834 | 0.80 | MAPT (0.52) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13886340 | 0.78 | MAPT (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869629 | 0.77 | MAPT (0.55) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869797 | 0.77 | CYP19A1 (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869702 | 0.77 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869801 | 0.76 | CYP19A1 (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869794 | 0.75 | ALDH1A1 (0.71) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13869678 | 0.75 | MAPT (0.50) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |