Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869818 | 0.92 | ALOX5AP (0.40) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL13869468 | 0.91 | ALOX5AP (0.40) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL13869827 | 0.90 | MAPT (0.43) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL13869843 | 0.82 | MAPT (0.39) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL13869452 | 0.82 | PIM1 (0.42) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL13869282 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HPGDMAPT | |
| SCHEMBL13869814 | 0.80 | MAPT (0.60) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL13869378 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL13869474 | 0.79 | MAPT (0.59) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL13869617 | 0.78 | KDM4E (0.44) | ALDH1A1KDM4EHPGDLMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |