Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869828 | 0.90 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869818 | 0.89 | ALOX5AP (0.40) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869468 | 0.88 | ALOX5AP (0.40) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869541 | 0.85 | MAPT (0.40) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869814 | 0.82 | MAPT (0.60) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869474 | 0.81 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869280 | 0.80 | SIRT2 (0.42) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869835 | 0.79 | PIM1 (0.35) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869843 | 0.79 | MAPT (0.39) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL13869452 | 0.79 | PIM1 (0.42) | MAPTKDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |