Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TLR2 | O60603 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886691 | 0.84 | CXCR2 (0.61) | PDE4DCNR2ALDH1A1TLR2HPGD | |
| SCHEMBL3986607 | 0.82 | MAPT (0.57) | PDE4DCNR2ALDH1A1TLR2MAPT | |
| SCHEMBL13869873 | 0.82 | ALDH1A1 (0.52) | CNR2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL3990554 | 0.78 | PDE4D (0.56) | PDE4DCNR2ALDH1A1TLR2MAPT | |
| SCHEMBL3984680 | 0.78 | MAPT (0.59) | PDE4DCNR2TLR2MAPTHPGD | |
| SCHEMBL13886693 | 0.78 | ALDH1A1 (0.49) | PDE4DCNR2ALDH1A1TLR2MAPT | |
| SCHEMBL3981360 | 0.76 | ALDH1A1 (0.52) | PDE4DCNR2ALDH1A1TLR2MAPT | |
| SCHEMBL13886694 | 0.72 | ALDH1A1 (0.48) | PDE4DCNR2ALDH1A1MAPTHPGD | |
| SCHEMBL3987266 | 0.72 | MAPT (0.48) | PDE4DCNR2ALDH1A1TLR2MAPT | |
| SCHEMBL6033998 | 0.71 | MAPT (0.52) | PDE4DCNR2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524853-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-04-28 | — | — | US | disclosed |
| US-7524853-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-04-28 | — | — | US | disclosed |
| US-7465739-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-16 | — | — | US | disclosed |
| US-7465739-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-16 | — | — | US | disclosed |