SCHEMBL13870138

SCHEMBL13870138

C[Si](C)(C)C1C/C(=C\c2ccc(N=[N+]=[N-])cc2)C(=O)/C(=C/c2ccc(N=[N+]=[N-])cc2)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.41
▸ RAB9A P51151 6/20 0.41
▸ NPC1 O15118 4/20 0.41
▸ HTT P42858 4/20 0.41
▸ MAPK1 P28482 3/20 0.41
▸ HSP90AA1 P07900 3/20 0.41
▸ CYP1A2 P05177 5/20 0.38
▸ PTGS2 P35354 1/20 0.36
▸ HSD11B1 P28845 3/20 0.36
▸ CYP2C9 P11712 2/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ PSMB8 P28062 1/20 0.35
▸ MITF O75030 1/20 0.35
▸ NSD2 O96028 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383522 0.95 CYP1A2 (0.47) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13858828 0.85 MAPT (0.55) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13861280 0.85 MAPT (0.55) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13886925 0.85 MAPT (0.55) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13882616 0.85 MAPT (0.55) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13886919 0.82 USP18 (0.54) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13886921 0.82 CA1 (0.38) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13737944 0.81 MAPT (0.50) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL17818209 0.81 MAPT (0.48) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL13870137 0.81 MAPT (0.38) MAPTRAB9ANPC1HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521744-B2 Resin-encapsulated semiconductor apparatus and process for its fabrication RENESAS TECHNOLOGY CORP. (JP) 2009-04-21 — — US disclosed
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