SCHEMBL30383522

SCHEMBL30383522

Cc1ccc(C=C2CC([Si](C)(C)C)CC(=Cc3ccc(N=[N+]=[N-])cc3)C2=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.47
▸ KMT2A Q03164 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ MAPT P10636 6/20 0.38
▸ RAB9A P51151 6/20 0.38
▸ NPC1 O15118 5/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ HTT P42858 2/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ MIF P14174 2/20 0.38
▸ ACHE P22303 3/20 0.36
▸ DHODH Q02127 1/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ PTGS2 P35354 1/20 0.34
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ MAOA P21397 1/20 0.33
▸ MAOB P27338 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13870138 0.95 MAPT (0.41) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL26395639 0.86 MAPT (0.50) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL30384724 0.85 USP18 (0.48) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL17625266 0.83 MAPT (0.46) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL30383935 0.82 F2 (0.51) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL30382045 0.82 F2 (0.51) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL13886925 0.80 MAPT (0.55) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL13861280 0.80 MAPT (0.55) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL13882616 0.80 MAPT (0.55) CYP1A2KMT2AMEN1MAPTRAB9A
SCHEMBL13858828 0.80 MAPT (0.55) CYP1A2KMT2AMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CYP1A2 541/4885KMT2A 2792/4885MEN1 3367/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CYP1A2 1041/4885KMT2A 3188/4885MEN1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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