Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927953 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL11382675 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL8482266 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL1548854 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL8482265 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| Ethane SCHEMBL7194508 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL8574539 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL1022607 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL15543861 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL28180523 | 0.80 | KDM4E (0.48) | TSHRALDH1A1TP53CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-115793391-A | Photoresist and application thereof | 北京科华微电子材料有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2020063999-A1 | MONO HALOGEN OR METHYL-SUBSTITUTED 5-HT2B ANTAGONISTS WITH INCREASED ACTIVITY | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2020-04-02 | — | — | WO | disclosed |
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |