SCHEMBL13870826

SCHEMBL13870826

COc1cc2cc(C)c(C)cc2nc1-c1cc(C)cc(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 4/20 0.39
▸ PDGFRA P16234 4/20 0.39
▸ NQO2 P16083 4/20 0.38
▸ MAPT P10636 2/20 0.38
▸ POLB P06746 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ G6PD P11413 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ HTT P42858 1/20 0.37
▸ AMY1A P0DUB6 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ PDE3B Q13370 2/20 0.36
▸ PDE3A Q14432 2/20 0.36
▸ CNR2 P34972 1/20 0.35
▸ ACHE P22303 1/20 0.34
▸ PDE10A Q9Y233 1/20 0.34
▸ PDE4A P27815 1/20 0.34
▸ PDE4D Q08499 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13399142 0.88 PDGFRB (0.37) PDGFRBPDGFRAMAPTNPC1LMNA
SCHEMBL13399656 0.88 PDGFRB (0.37) PDGFRBPDGFRANQO2MAPTPOLB
SCHEMBL13399622 0.84 PDGFRB (0.40) PDGFRBPDGFRAMAPTPOLBNPC1
SCHEMBL13870788 0.84 PDE10A (0.46) NQO2MAPTPOLBNPC1LMNA
SCHEMBL13647152 0.82 CYP1A2 (0.42) PDGFRBPDGFRAMAPTRAB9AHTT
SCHEMBL13870817 0.82 PDGFRB (0.44) PDGFRBPDGFRAMAPTHTTKDM4E
SCHEMBL12313241 0.82 EHMT2 (0.32) PDGFRBPDGFRAPOLBHTTPDE3B
SCHEMBL12313229 0.82 CYP19A1 (0.34) PDGFRBPDGFRANQO2MAPTPOLB
SCHEMBL13870823 0.80 PDE4A (0.40) NQO2MAPTPOLBNPC1LMNA
SCHEMBL13870824 0.79 PDE4A (0.42) PDGFRBPDGFRAMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 — — US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 — — US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 — — US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 PDGFRB 1748/4885PDGFRA 1137/4885NQO2 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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