Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.71 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.70 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503699 | 0.90 | GAA (1.00) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL13870855 | 0.88 | MEN1 (0.72) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL6348632 | 0.86 | MEN1 (0.69) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL14855642 | 0.86 | KMT2A (0.79) | ALDH1A1GAAKMT2AMEN1KCNK3 | |
| SCHEMBL15528812 | 0.86 | MAPK1 (0.71) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL16179842 | 0.83 | KMT2A (0.83) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL16179714 | 0.83 | MEN1 (1.00) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL29564094 | 0.83 | MEN1 (1.00) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL18906020 | 0.83 | RAB9A (0.79) | ALDH1A1GAAKMT2AMEN1SIRT6 | |
| SCHEMBL13870842 | 0.81 | KMT2A (0.67) | ALDH1A1GAAKMT2AMEN1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | ALDH1A1 787/4885GAA 4471/4885KMT2A 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.