Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 1.00 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564094 | 1.00 | MEN1 (1.00) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL16179842 | 0.91 | KMT2A (0.83) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL16179518 | 0.90 | SIRT6 (1.00) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL13870855 | 0.84 | MEN1 (0.72) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL13870838 | 0.83 | ALDH1A1 (0.81) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL18906020 | 0.83 | RAB9A (0.79) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL16179844 | 0.81 | SIRT6 (1.00) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL3503699 | 0.81 | GAA (1.00) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL6348632 | 0.80 | MEN1 (0.69) | MEN1KMT2ASIRT6SIRT3POLB | |
| SCHEMBL1129948 | 0.79 | KMT2A (0.77) | MEN1KMT2ASIRT6SIRT3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170873-A1 | COMPOUNDS WITH A SIRTUIN INHIBITING ACTIVITY | UNIVERSITÀ DEGLI STUDI DI GENOVA (IT) | 2014-10-23 | — | — | WO | claimed |
| EP-4646195-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING GLUCOSE LEVELS | Sirtsei Pharmaceuticals, Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4637742-A1 | COMPOSITIONS AND METHODS FOR TREATING ANHEDONIA | Sirtsei Pharmaceuticals, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250114400-A1 | Application of SIRT1-7 protein in immunotherapy | Avenex Biosciences LTD. (CN) | 2025-04-10 | — | — | US | disclosed |
| WO-2024168215-A1 | COMPOSITIONS AND METHODS FOR TREATING ANHEDONIA | SIRTSEI PHARACEUTICALS, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-116426483-B | Application of CD258 protein in immunotherapy | 南京紫珑生物科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-116426483-A | Application of CD258 protein in immunotherapy | 南京紫珑生物科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116411025-A | Application of SIRT1-7 protein in immunotherapy | 南京紫珑生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| WO-2023123225-A1 | APPLICATION OF SIRT1-7 PROTEIN IN IMMUNOTHERAPY | 南京紫珑生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125945-A1 | USE OF CD258 PROTEIN IN IMMUNOTHERAPY | 南京紫珑生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2014170873-A1 | COMPOUNDS WITH A SIRTUIN INHIBITING ACTIVITY | UNIVERSITÀ DEGLI STUDI DI GENOVA (IT) | 2014-10-23 | — | — | WO | disclosed |