Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.81 |
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | RPA1 | P27694 | 2/20 | 0.74 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | PTGES | O14684 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870863 | 0.89 | MEN1 (1.00) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL13870878 | 0.86 | MEN1 (0.88) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL13870884 | 0.86 | MEN1 (0.88) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL13870868 | 0.85 | RPA1 (1.00) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL13870881 | 0.85 | MEN1 (0.86) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL12431833 | 0.85 | MEN1 (0.80) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL16353693 | 0.82 | MAPT (0.61) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL29698008 | 0.82 | MAPT (0.61) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL14075286 | 0.81 | MEN1 (0.86) | MEN1KMT2ANPC1RPA1GFER | |
| SCHEMBL13870887 | 0.80 | MEN1 (0.82) | MEN1KMT2ANPC1RPA1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | MEN1 2859/4885KMT2A 2570/4885NPC1 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.