Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RPA1 | P27694 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353693 | 1.00 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL14291954 | 0.86 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL13870883 | 0.82 | MEN1 (0.81) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16386084 | 0.77 | NPC1 (0.54) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6403077 | 0.77 | KMT2A (0.81) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL27180424 | 0.76 | IDH1 (0.62) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17179708 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13870881 | 0.76 | MEN1 (0.86) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL15919822 | 0.75 | MEN1 (0.78) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL13870884 | 0.74 | MEN1 (0.88) | MAPTMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065224-A1 | USE OF NEUROPILIN ANTAGONISTS FOR THE TREATMENT OF ENDOMETRIOSIS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2022-10-05 | — | — | EP | disclosed |
| EP-3980012-A1 | A NEUROPILIN ANTAGONIST IN COMBINATION WITH A P38ALPHA-KINASE INHIBITOR FOR THE TREATMENT OF CANCER | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2022-04-13 | — | — | EP | disclosed |