Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 20/20 | 0.89 |
| ▸ | MTNR1A | P48039 | 19/20 | 0.89 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567415 | 0.93 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL1567007 | 0.93 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL338730 | 0.82 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL29827337 | 0.82 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| Ramelteon SCHEMBL29237 | 0.82 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| Ramelteon SCHEMBL29380213 | 0.82 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL1566122 | 0.82 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL1612991 | 0.81 | MTNR1A (0.78) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL3071955 | 0.80 | MTNR1A (0.76) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL14863848 | 0.80 | MTNR1A (0.76) | MTNR1BMTNR1AABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10502336-A | — | — | 1998-03-03 | — | — | JP | claimed |
| EP-0821681-A1 | NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| WO-1995029173-A1 | NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 1995-11-02 | — | — | WO | claimed |