Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945481 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| SCHEMBL10726585 | 0.76 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| SCHEMBL6773584 | 0.75 | — | — | |
| SCHEMBL11584636 | 0.75 | — | — | |
| SCHEMBL4790582 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10726402 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| SCHEMBL10293223 | 0.74 | — | — | |
| SCHEMBL24133884 | 0.74 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| SCHEMBL10730506 | 0.73 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTCYP2D6SMN1; SMN2 | |
| Bromide SCHEMBL11700718 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093452-A1 | Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives | PFIZER INC. | 2009-04-09 | — | — | US | disclosed |
| US-20080076813-A1 | Benzene, Pyridine, and Pyridazine Derivatives | SERENEX, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076813-A1 | Benzene, Pyridine, and Pyridazine Derivatives | MKI67, CCNB1, CCNB3 | ALDH1A1 580/4885GAA 4387/4885MAPT 3953/4885 |
| US-20090093452-A1 | Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives | JAK3, JAK2, FLT4 | ALDH1A1 1279/4885GAA 4028/4885MAPT 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.