Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792579 | 0.90 | HTT (0.58) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL27004615 | 0.89 | HTT (0.62) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL15545516 | 0.83 | HTT (0.55) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL28334704 | 0.82 | KDM4E (0.68) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL8655345 | 0.81 | KDM4E (0.66) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL8879807 | 0.79 | KDM4E (1.00) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL17702625 | 0.78 | KMT2A (0.70) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL22886505 | 0.77 | HTT (0.49) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL6274755 | 0.77 | KMT2A (0.69) | HTTKDM4EKMT2AMEN1HSD11B1 | |
| SCHEMBL17703564 | 0.77 | KDM4E (0.60) | HTTKDM4EKMT2AMEN1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090110634-A1 | RADIOLABELLED NANOPARTICLES | BEER PAUL D | 2009-04-30 | — | — | US | disclosed |
| US-20090110634-A1 | RADIOLABELLED NANOPARTICLES | BEER PAUL D | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090110634-A1 | RADIOLABELLED NANOPARTICLES | CD63, PIGO, NCL | HTT 1553/4885KDM4E 3053/4885KMT2A 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.