Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL122180 | 1.00 | — | — | |
| Bicarbonate SCHEMBL231029 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10889913 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3825097 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2179586 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL290407 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2504262 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15955618 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL290408 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8817830 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462111-A | Multi-element rare earth silicate/silicon oxygen carbon nano multiphase ceramic and preparation method thereof | 中南大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118006329-A | Lutetium calcium indium gallium zirconium garnet Dan Jilan light fluorescent powder and application thereof | 广州医科大学附属口腔医院（广州医科大学羊城医院） | 2024-05-10 | — | — | CN | claimed |
| CN-117926221-A | Device for forming corrosion-resistant coating and method for forming corrosion-resistant coating | 中微半导体设备(上海)股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-115259206-B | Preparation method of high-purity thulium carbonate and high-purity thulium trifluoride | 承德莹科精细化工股份有限公司 | 2024-02-20 | — | — | CN | claimed |
| US-11865509-B2 | Porous molding | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-01-09 | — | — | US | claimed |
| CN-116334418-B | Defluorination method for ionic rare earth cascade extraction production line soap stock | 定南大华新材料资源有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-113631257-B | Blood purifier and method for manufacturing the same | 旭化成医疗株式会社 | 2023-06-30 | — | — | CN | claimed |
| CN-116334418-A | Defluorination method for ionic rare earth cascade extraction production line soap stock | 定南大华新材料资源有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115558497-A | Dy-based composite material 3+ And Tm 3+ Coactivated phosphate material, preparation method and application thereof | 中山大学 | 2023-01-03 | — | — | CN | claimed |
| CN-115259206-A | Preparation method of high-purity thulium carbonate and high-purity thulium trifluoride | 承德莹科精细化工股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-102179024-A | Fire extinguishing composition for generating fire extinguishing substance through chemical reaction among components at high temperature | SHAN XI J & R FIRE PROT CO LTD | 2011-09-14 | — | — | CN | claimed |
| CN-102179026-A | Fire extinguishing composition generating extinguishant by pyrolysis | SHAANXI J & R FIRE FIGHTING CO | 2011-09-14 | — | — | CN | claimed |
| CN-102146286-A | Tungstate matrix upper conversion white light emitting material and preparation method thereof | UNIV CHINA GEOSCIENCES WUHAN | 2011-08-10 | — | — | CN | claimed |
| CN-101362605-B | Rare-earth nano oxide preparation method | CHANGCHUN APPLIED CHEMISTRY | 2011-05-18 | — | — | CN | claimed |
| CN-101700902-B | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERIAL CO LTD | 2011-05-04 | — | — | CN | claimed |
| CN-101700902-A | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERI | 2010-05-05 | — | — | CN | claimed |
| CN-101362605-A | Rare-earth nano oxide preparation method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-02-11 | — | — | CN | claimed |
| CN-101177612-A | Praseodymium doped red long-afterglow luminescent material and preparation method thereof | BAOTOU RARE EARTH RES INST (CN) | 2008-05-14 | — | — | CN | claimed |
| WO-2005054132-A1 | TAGGED POLYMERIC MATERIALS AND METHODS FOR THEIR PREPARATION | ORICA AUSTRALIA PTY LTD (AU) | 2005-06-16 | — | — | WO | claimed |
| US-4211882-A | OXIDIZING P-TOLUALDEHYDE, CATALYST CONSISTING OF A MANGANESE COMPOUND, A COBALT COMPOUND, A BROMINE COMPOUND, AND A NICKEL, IRON, CHROMIUM, OR LANTHANIDE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-08 | — | — | US | claimed |