Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL122180 | 0.94 | — | — | |
| Bicarbonate SCHEMBL138735 | 0.94 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL15955618 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL10889913 | 0.88 | — | — | |
| Bicarbonate SCHEMBL8817830 | 0.88 | — | — | |
| Bicarbonate SCHEMBL290408 | 0.88 | — | — | |
| Bicarbonate SCHEMBL290407 | 0.88 | — | — | |
| Bicarbonate SCHEMBL6705662 | 0.88 | — | — | |
| Bicarbonate SCHEMBL231029 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL2179586 | 0.88 | CA4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613785-B1 | REDUCTIVE AMMONIACAL LEACHING OF NICKEL AND COBALT BEARING MATERIALS | BHP BILLITON SSM DEV PTY LTD (AU) | 2013-03-13 | — | — | EP | disclosed |
| US-7601314-B2 | Recovery of nickel and/or cobalt from an impure nickel, cobalt or mixednickel/cobalt material by contacting with a feed ammoniacal ammonium carbonate solution and a reductant in aleach step, where the reductant is selected from a mixed cobalt/nickelsulfide, cobalt sulfide or hydroxylamine; Caron process | BHP BILLITON SSM TECHNOLOGY PTY LTD (AU) | 2009-10-13 | — | — | US | disclosed |
| EP-1613785-A4 | REDUCTIVE AMMONIACAL LEACHING OF NICKEL AND COBALT BEARING MATERIALS | BHP BILLITON SSM TECH PTY LTD (AU) | 2008-05-28 | — | — | EP | disclosed |
| US-20070166214-A1 | Reductive ammoniacal leaching of nickel and coblat bearing | BHP BILLITON SSM DEVELOPMENT PTY LTD (AU) | 2007-07-19 | — | — | US | disclosed |
| EP-1613785-A1 | REDUCTIVE AMMONIACAL LEACHING OF NICKEL AND COBALT BEARING MATERIALS | BHP Billiton SSM Technology Pty Ltd. (AU) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004090176-A1 | REDUCTIVE AMMONIACAL LEACHING OF NICKEL AND COBALT BEARING MATERIALS | BHP BILLITON SSM TECHNOLOGY PTY LTD (AU) | 2004-10-21 | — | — | WO | disclosed |