SCHEMBL138742

SCHEMBL138742

CC(C)(C(=O)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
TSHR P16473 4/20 0.33
ALDH1A1 P00352 3/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.31
PKM P14618 1/20 0.31
PTK2B Q14289 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154133 0.81 TSHR (0.38) THRBTSHRALDH1A1TP53
SCHEMBL15187619 0.79 TSHR (0.33) THRBTSHRALDH1A1TP53
SCHEMBL569122 0.77
SCHEMBL94994 0.77
SCHEMBL28528092 0.76 TSHR (0.47) THRBTSHRALDH1A1TP53CYP1A2
SCHEMBL30299516 0.76 THRB (0.39) THRBTSHRALDH1A1TP53CYP1A2
SCHEMBL140224 0.74
SCHEMBL10544155 0.74 TSHR (0.36) THRBTSHRALDH1A1TP53CYP1A2
SCHEMBL11673323 0.74 TSHR (0.36) THRBTSHRALDH1A1TP53
SCHEMBL29113018 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112250559-B Recycling process of chloro pivaloyl chloride raffinate 王泽萱 2024-05-03 CN claimed
CN-112250559-A Process for recycling chloro pivaloyl chloride residual liquid 刘光辉 2021-01-22 CN claimed
JP-4838706-B2 2011-12-14 JP claimed
EP-1776375-A2 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2007-04-25 EP claimed
WO-2006016997-A2 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2006-02-16 WO claimed
EP-1589934-A2 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2005-11-02 EP claimed
US-20050227943-A1 Certain aminoalkyl glucosaminide phosphate compounds and their use CORIXA CORPORATION (US) 2005-10-13 US claimed
WO-2004062599-A2 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2004-07-29 WO claimed
CN-112250559-B Recycling process of chloro pivaloyl chloride raffinate 王泽萱 2024-05-03 CN disclosed
CN-214937126-U Chloro pivaloyl chloride waste liquid decoloration device 山东民基新材料科技有限公司 2021-11-30 CN disclosed
CN-112250559-A Process for recycling chloro pivaloyl chloride residual liquid 刘光辉 2021-01-22 CN disclosed
EP-2940028-B1 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORP (US) 2017-08-16 EP disclosed
EP-2940027-A1 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2015-11-04 EP disclosed
EP-2940028-A1 CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE CORIXA CORPORATION (US) 2015-11-04 EP disclosed
US-4609648-A SYNERGISTS FOR ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-09-02 US disclosed
EP-0132733-B1 FLUOROPIVALIC-ACID FLUORIDES AND PROCESS FOR PRODUCING THEM BAYER AG (DE) 1986-06-11 EP disclosed
US-4549994-A INTERMEDIATES FOR MAKING CARBAMATE INSECTICIDE SYNERGISTS BAYER AKTIENGESELLSCHAFT (DE) 1985-10-29 US disclosed
EP-0132729-A2 Halogenoalkylcarbamic-acid esters, their preparation and their use as pesticides BAYER AG (DE) 1985-02-13 EP disclosed
EP-0132734-A2 Neopentyl isocyanates and their preparation BAYER AG (DE) 1985-02-13 EP disclosed
EP-0132733-A2 Fluoropivalic-acid fluorides and process for producing them BAYER AG (DE) 1985-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227943-A1 Certain aminoalkyl glucosaminide phosphate compounds and their use IFNG, CD68, IL2 THRB 2290/4885TSHR 3657/4885ALDH1A1 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.