Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.73 |
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | CCNC | P24863 | 1/20 | 0.73 |
| ▸ | CDK8 | P49336 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076850 | 0.84 | LMNA (1.00) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL4359487 | 0.84 | HTT (1.00) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL4359385 | 0.82 | HTT (0.83) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL13283258 | 0.82 | LMNA (0.83) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL4366081 | 0.81 | HTT (0.72) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL13621680 | 0.81 | HTT (0.72) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL13283263 | 0.81 | HTT (0.72) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL15056713 | 0.81 | HTT (0.81) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL13621683 | 0.80 | RXFP1 (0.79) | HTTLMNAMAPTCCNCCDK8 | |
| SCHEMBL13283269 | 0.80 | HTT (0.76) | HTTLMNAMAPTCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |