Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.84 |
| ▸ | HTR1A | P08908 | 10/20 | 0.60 |
| ▸ | HTR1D | P28221 | 10/20 | 0.60 |
| ▸ | HTR1B | P28222 | 10/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7813268 | 0.98 | SLC6A9 (0.82) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL8185864 | 0.92 | SLC6A9 (0.83) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7810671 | 0.91 | SLC6A9 (0.82) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL7813346 | 0.91 | SLC6A9 (0.76) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7813281 | 0.90 | SLC6A9 (0.96) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1387634 | 0.89 | SLC6A9 (0.74) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7810308 | 0.88 | SLC6A9 (0.72) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL7803817 | 0.86 | SLC6A9 (0.70) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL8780741 | 0.85 | SLC6A9 (0.71) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1387788 | 0.85 | SLC6A9 (0.68) | SLC6A9KCNH2HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767782-B1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | claimed |
| JP-H09506638-A | — | — | 1997-06-30 | — | — | JP | claimed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | claimed |
| WO-2020183011-A1 | HTR1D INHIBITORS AND USES THEREOF IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2020-09-17 | — | — | WO | disclosed |
| EP-0767782-B1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6166020-A | Aryl and heteroaryl alkoxynaphthalene derivatives | PFIZER INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | disclosed |