Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | HTR1A | P08908 | 11/20 | 0.56 |
| ▸ | HTR1D | P28221 | 10/20 | 0.56 |
| ▸ | HTR1B | P28222 | 10/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1387548 | 0.98 | SLC6A9 (0.69) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL1387524 | 0.85 | SLC6A9 (0.84) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL1387568 | 0.85 | SLC6A9 (0.51) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7813268 | 0.84 | SLC6A9 (0.82) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL8185864 | 0.83 | SLC6A9 (0.83) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL7813346 | 0.82 | SLC6A9 (0.76) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7810671 | 0.82 | SLC6A9 (0.82) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL7803817 | 0.81 | SLC6A9 (0.70) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7813281 | 0.81 | SLC6A9 (0.96) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1387634 | 0.81 | SLC6A9 (0.74) | SLC6A9KCNH2HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | claimed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | disclosed |