SCHEMBL13875337

SCHEMBL13875337

O=NCc1cccc(CN=O)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.52
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
GRIN3A Q8TCU5 1/20 0.50
PGK1 P00558 1/20 0.43
PGK2 P07205 1/20 0.43
KCNH2 Q12809 5/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CXCR4 P61073 2/20 0.35
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.32
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
SCN5A Q14524 1/20 0.31
CYP3A4 P08684 2/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18519069 0.74 HSD17B14 (0.38) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1166481 0.73
Ammonia Solution, Strong SCHEMBL6808558 0.72 HRH1 (0.47) LMNAALDH1A1
SCHEMBL45869 0.69 KCNH2 (0.52) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15259719 0.69 HRH4 (0.47) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11564452 0.67 KCNH2 (0.50) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6404034 0.66 PARP1 (0.38) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2096973 0.65 KCNH2 (0.43) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL943002 0.65 CCR1 (0.48) HRH4GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL17230076 0.65 GRIN2B (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2042312-B1 Processing method of lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-2042312-A2 Processing method of lithographic printing plate precursor FUJIFILM Corporation (JP) 2009-04-01 EP disclosed