Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.79 |
| ▸ | GNG2 | P59768 | 5/20 | 0.67 |
| ▸ | GNB1 | P62873 | 5/20 | 0.67 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.65 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402943 | 0.89 | PHLPP2 (0.66) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL29666889 | 0.88 | PHLPP2 (1.00) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL9173299 | 0.88 | PHLPP2 (1.00) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL14133655 | 0.88 | PHLPP2 (0.60) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL2854079 | 0.87 | PHLPP2 (0.98) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL10782615 | 0.87 | PHLPP2 (0.74) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL9136312 | 0.87 | GNG2 (0.75) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL8402397 | 0.86 | PHLPP2 (0.84) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL11443152 | 0.86 | GNG2 (0.73) | PHLPP2GNG2GNB1P2RY2P2RY4 | |
| SCHEMBL11311121 | 0.85 | PHLPP2 (0.82) | PHLPP2GNG2GNB1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090100611-A1 | Acid Dye Composition of Anthraquinone Dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-04-23 | — | — | US | disclosed |
| US-20070226919-A1 | Method for Dyeing or Printing Textile Materials | HUNTSMAN INTERNATIONAL LLC (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007028665-A1 | ACID DYE COMPOSITION OF ANTHRAQUINONE DYES | CLARIANT INTERNATIONAL LTD (CH) | 2007-03-15 | — | — | WO | disclosed |