SCHEMBL9173299

SCHEMBL9173299

CC(=O)Nc1ccc(Nc2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 2/20 1.00
▸ P2RY2 P41231 8/20 0.82
▸ GNG2 P59768 5/20 0.77
▸ GNB1 P62873 5/20 0.77
▸ CYP1A2 P05177 2/20 0.67
▸ CYP2C9 P11712 2/20 0.67
▸ ALOX15 P16050 2/20 0.67
▸ HSD17B10 Q99714 2/20 0.67
▸ P2RY4 P51582 8/20 0.64
▸ ALDH1A1 P00352 1/20 0.63
▸ CYP3A4 P08684 1/20 0.63
▸ HPGD P15428 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ CYP2C19 P33261 1/20 0.63
▸ HIF1A Q16665 1/20 0.63
▸ P2RY12 Q9H244 5/20 0.60
▸ P2RY6 Q15077 3/20 0.60
▸ ENTPD1 P49961 2/20 0.60
▸ MET P08581 2/20 0.60
▸ HGF P14210 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666889 1.00 PHLPP2 (1.00) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL2854079 0.99 PHLPP2 (0.98) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL8402397 0.91 PHLPP2 (0.84) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL13021512 0.91 GNG2 (0.92) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL11311937 0.91 PHLPP2 (0.82) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL11311121 0.90 PHLPP2 (0.82) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL29356677 0.89 P2RY2 (1.00) PHLPP2P2RY2P2RY4P2RY12P2RY6
SCHEMBL13875739 0.88 PHLPP2 (0.79) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL2779595 0.87 GNG2 (1.00) PHLPP2P2RY2GNG2GNB1CYP1A2
SCHEMBL9137161 0.87 GNG2 (0.82) PHLPP2P2RY2GNG2GNB1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108147310-A A kind of carbon tetrachloride processing centrifuge movement maintenance unit 徐州工程学院 2018-06-12 — — CN claimed
JP-58125755-A — — None — — JP disclosed
JP-58125758-A — — None — — JP disclosed
JP-55133461-A — — None — — JP disclosed
US-20200360392-A1 DIGALLIC ACID FOR REDUCTION OF INFLAMMATORY CYTOKINE ACTIVITY ENZO BIOCHEM, INC (US) 2020-11-19 — — US disclosed
US-20190350936-A1 METHOD FOR PROMOTING WOUND HEALING BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN ENZO BIOCHEM, INC. (US) 2019-11-21 — — US disclosed
CN-108147310-A A kind of carbon tetrachloride processing centrifuge movement maintenance unit 徐州工程学院 2018-06-12 — — CN disclosed
US-20170020883-A1 METHOD FOR PROMOTING WOUND HEALING BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN ENZO BIOCHEM, INC. (US) 2017-01-26 — — US disclosed
US-20170020883-A1 METHOD FOR PROMOTING WOUND HEALING BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN ENZO BIOCHEM, INC. (US) 2017-01-26 — — US disclosed
CN-106315805-A Modified straw polypropylene composite flocculant and key production technology thereof 徐州工程学院 2017-01-11 — — CN disclosed
US-20110049444-A1 COLORED RESIN COMPOSITIONS FOR COLOR FILTER, COLOR FILTER, ORGANIC EL DISPLAY, AND LIQUID-CRYSTAL DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-03-03 — — US disclosed
US-20090100611-A1 Acid Dye Composition of Anthraquinone Dyes CLARIANT FINANCE (BVI) LIMITED (VG) 2009-04-23 — — US disclosed
WO-2007028665-A1 ACID DYE COMPOSITION OF ANTHRAQUINONE DYES CLARIANT INTERNATIONAL LTD (CH) 2007-03-15 — — WO disclosed
US-5385842-A Anthraquinones as inhibitors of sulfide production from sulfate-reducing bacteria E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-31 — — US disclosed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 — — EP disclosed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 — — EP disclosed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 — — WO disclosed
JP-S58125755-A ANTHRAQUINONE-TYPE ANIONIC DYE COMPOSITION SUMITOMO CHEM CO LTD 1983-07-26 — — JP disclosed
JP-S58125758-A ANIONIC DYE COMPOSITION SUMITOMO CHEM CO LTD 1983-07-26 — — JP disclosed
JP-S55133461-A ANIONIC DYE FORMULATION SUMITOMO CHEM CO LTD 1980-10-17 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360392-A1 DIGALLIC ACID FOR REDUCTION OF INFLAMMATORY CYTOKINE ACTIVITY LRP6, IL6, IL6ST PHLPP2 1769/4885P2RY2 1349/4885GNG2 1011/4885
US-20190350936-A1 METHOD FOR PROMOTING WOUND HEALING BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN LDLR, LRP6, LPAR6 PHLPP2 505/4885P2RY2 1674/4885GNG2 930/4885
US-20170020883-A1 METHOD FOR PROMOTING WOUND HEALING BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN LDLR, LRP6, LPAR6 PHLPP2 505/4885P2RY2 1674/4885GNG2 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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