Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701786 | 0.85 | CD274 (0.51) | GAASMN1; SMN2KDM4EALDH1A1CD274 | |
| SCHEMBL14058966 | 0.85 | KDM4E (0.55) | GAASMN1; SMN2KDM4EALDH1A1CD274 | |
| SCHEMBL13702364 | 0.83 | CD274 (0.53) | GAASMN1; SMN2KDM4EALDH1A1CD274 | |
| SCHEMBL12632239 | 0.83 | SMN1; SMN2 (0.70) | GAASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13875983 | 0.82 | SMN1; SMN2 (0.48) | GAASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13702310 | 0.81 | CD274 (0.57) | GAASMN1; SMN2KDM4EALDH1A1CD274 | |
| SCHEMBL13702141 | 0.81 | HRH3 (0.60) | GAASMN1; SMN2KDM4EALDH1A1CD274 | |
| SCHEMBL26172916 | 0.80 | OPRM1 (0.44) | KDM4E | |
| SCHEMBL9906399 | 0.79 | SIGMAR1 (0.50) | KDM4EALDH1A1POLBTSHR | |
| SCHEMBL29036808 | 0.77 | ATM (0.51) | KDM4EALDH1A1KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | GAA 1180/4885SMN1; SMN2 4349/4885KDM4E 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.